Levomepromazine (Nozinan)


Overview: Levomepromazine, known by the brand name Nozinan, is an antipsychotic of the Typical class. Levomepromazine is used to treat Psychosis – including Schizophrenia and the manic phase of Bipolar Disorder. Levomepromazine can also be used as a pain relief for terminally ill patients. Levomepromazine has helped many people control their symptoms. Due to its intense side effects, Levomepromazine is normally one of the last antipsychotics prescribed. Levomepromazine is only available on prescription.


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Key Facts: It will take around four to six weeks for a patient to feel the full benefits of Levomepromazine. However, anxiety should lessen rapidly upon consumption of the drug. There are some side effects to Levomepromazine, as mentioned below. Levomepromazine should be used without interruption – you shouldn’t suddenly stop taking the medicine. The medicine should help control your symptoms.


How do they work?: Antipsychotics cannot help cure mental health conditions, but they are usually effective in reducing and controlling some of the symptoms associated with these conditions. These symptoms can include delusions and hallucinations, disturbed thoughts, agitation, mania and violence. The medication works by blocking the action of dopamine. It is believed psychotic episodes are caused by the brain producing too much of the chemical dopamine. The medication also regulates levels of other chemicals that are responsible for regulating mood – such as noradrenaline and serotonin. It is recommended that Levomepromazine is used in conjunction with therapy.


Dosage: The regular dose of Levomepromazine is 25mg-50mg per day. This will be split between 1 or 2 tablets a day, though in some cases up to 8 tablets a day will be prescribed. You should swallow each tablet whole with a glass of water. Your doctor will prescribe the dose required to treat your condition. A typical treatment course of Levomepromazine can range from patient to patient, dependent on circumstance and the severity of symptoms.


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Side Effects

With each box of Levomepromazine, there will be an information leaflet enclosed. This will provide an exhaustive list of side effects. Side effects from Levomepromazine can last any length of time from just a few days to permanent changes. It is natural to experience some side effects as your body gets used to the medication.


Common side effects of Levomepromazine include restlessness, shaking, a dry mouth, fast heartbeat, night sweats and weight gain.


Serious side effects include suicidal thinking, tremors, constipation, heart palpitations and jaundice. An overdose should be avoided. You should contact your doctor if any of these serious side effects take place.




You should always read the information leaflet that comes with your medication as it will include important information there. You should tell your doctor if you are taking any other medication. You shouldn’t use any other antipsychotic medication with Levomepromazine. Do not use any antipsychotic with Tricyclic Antidepressants. The medicine Desferrioxamine shouldn’t be combined with Levomepromazine.


If you suffer from Parkinson’s disease, have liver problems, blood clots, diabetes, epilepsy or an alcohol addiction, avoid using Levomepromazine.


Alcohol acts as a sedative, therefore it is recommended that anyone taking an antipsychotic stays away from drinking alcohol. Combining Levomepromazine with recreational drugs is also not recommended.


Levomepromazine is not recommended in pregnancy or the breastfeeding stage. It is believed that Levomepromazine can cause withdrawal symptoms in breastfed babies.


Other Typical Antipsychotics: