Lurasidone (Latuda)


Overview: Lurasidone, known by the brand name Latuda, is an antipsychotic of the Atypical class – the most frequently used class of antipsychotics. Lurasidone is used to treat Psychosis – including Schizophrenia. Lurasidone has helped many people control their symptoms, and is one of the youngest antipsychotics. Lurasidone is only available on prescription.


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Key Facts: It will take around four to six weeks for a patient to feel the full benefits of Lurasidone. However, anxiety should lessen rapidly upon consumption of the drug. There are some side effects to Lurasidone, as mentioned below. Lurasidone should be used without interruption – you shouldn’t suddenly stop taking the medicine. The medicine should help control your symptoms.


How do they work?: Antipsychotics cannot help cure mental health conditions, but they are usually effective in reducing and controlling some of the symptoms associated with these conditions. These symptoms can include delusions and hallucinations, disturbed thoughts, agitation, mania and violence. The medication works by blocking the action of dopamine. It is believed psychotic episodes are caused by the brain producing too much of the chemical dopamine. The medication also regulates levels of other chemicals that are responsible for regulating mood – such as noradrenaline and serotonin. It is recommended that Lurasidone is used in conjunction with therapy.


Dosage: The regular dose of Lurasidone in adults is 37mg per day. This however is often raised gradually over a period of a few weeks. You can take the tablet in one sitting. The maximum dose per day is 148mg. Lurasidone has a very bitter taste, so you should swallow it with water. You must take Lurasidone with food or just after eating. There is no set duration of treatment for Lurasidone, with the course differing from patient to patient, dependent on circumstance and symptoms.


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Side Effects

With each box of Lurasidone, there will be an information leaflet enclosed. This will provide an exhaustive list of side effects. Side effects from Lurasidone can last any length of time from just a few days to permanent changes. It is natural to experience some side effects as your body gets used to the medication.


Common side effects of Lurasidone include restlessness, sleepiness, shaking, speech problems, dizziness, muscle spasms, dry mouth, weight gain, blurred vision.


Serious side effects include suicidal thinking, chest pain, movement disorders, seizures, jaundice, blood clots. An overdose should be avoided. You should contact your doctor if any of these serious side effects take place.




You should always read the information leaflet that comes with your medication as it will include important information there. You should tell your doctor if you are taking any other medication. You shouldn’t use any other antipsychotic medication with Lurasidone. Do not use any antipsychotic with Tricyclic Antidepressants. Medicines for Parkinson’s disease and blood pressure can react poorly with Lurasidone. Always ask your doctor about combining medications.


Do not take Lurasidone if you are taking any medicines that will affect the amount of Lurasidone in your blood. Some medicines such as antibiotics and the herbal remedy St. John’s Wort will be unsuitable for co-administration with Lurasidone.


Exert caution when using Lurasidone if you have Parkinson’s disease, any movement disorder, any heart problem, convulsions, diabetes, liver or kidney problems or blood pressure issues.


Alcohol acts as a sedative, therefore it is recommended that anyone taking an antipsychotic doesn’t consume alcohol. Do not drink grapefruit juice while taking Lurasidone. Combining Lurasidone with recreational drugs is also not recommended.


Lurasidone  is not recommended in pregnancy or the breastfeeding stage. It is believed that Lurasidone can cause withdrawal symptoms in breastfed babies.


Other Atypical Antipsychotics: