Overview: Promazine is an antipsychotic of the Typical class. Promazine is used to treat Psychosis – mainly Schizophrenia, and sometimes anxiety. Promazine has helped many people control their symptoms. Promazine is only available on prescription. Promazine is very rarely used in the contemporary age, and doesn’t have a license for human use in the United States.


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Key Facts: It will take around four to six weeks for a patient to feel the full benefits of Promazine. However, anxiety should lessen rapidly upon consumption of the drug. There are some side effects to Promazine, as mentioned below. Promazine should be used without interruption – you shouldn’t suddenly stop taking the medicine. The medicine should help control your symptoms.


How do they work?: Antipsychotics cannot help cure mental health conditions, but they are usually effective in reducing and controlling some of the symptoms associated with these conditions. These symptoms can include delusions and hallucinations, disturbed thoughts, agitation, mania and violence. The medication works by blocking the action of dopamine. It is believed psychotic episodes are caused by the brain producing too much of the chemical dopamine. The medication also regulates levels of other chemicals that are responsible for regulating mood – such as noradrenaline and serotonin. It is recommended that Promazine is used in conjunction with therapy.


Dosage: Promazine comes in the form of a liquid syrup. The normal dose of Promazine is between 100mg and 200mg per day – taken four times a day. However you will likely begin on a lower dose. Your doctor will advise you on how to take Promazine. A typical treatment course of Promazine can depend on many circumstances and the symptoms of a condition.


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Side Effects

With each box of Promazine, there will be an information leaflet enclosed. This will provide an exhaustive list of side effects. Side effects from Promazine can last any length of time from just a few days to permanent changes. It is natural to experience some side effects as your body gets used to the medication.


Common side effects of Promazine include a dry mouth, drowsiness, sleepiness, insomnia, breast enlargement in men, headache, sexual dysfunction, weight gain and constipation.


Serious side effects include suicidal thinking, abnormally fast heartbeat, seizures, blood problems, movement disorders, blurred vision, confusion and jaundice. An overdose should be avoided. You should contact your doctor if any of these serious side effects take place.




You should always read the information leaflet that comes with your medication as it will include important information there. You should tell your doctor if you are taking any other medication. You shouldn’t use any other antipsychotic medication with Promazine. Do not use any antipsychotic with Tricyclic Antidepressants. Other medicines that you shouldn’t combine with Promazine include Quinidine, medicines for Parkinson’s Disease, malaria, stomach problems, diabetes, painkillers and Kaolin.


Don’t take Promazine if you suffer from bone marrow depression, have liver or kidney problems, jaundice, blood problems, heart problems, Parkinson’s disease, breathing problems, epilepsy or glaucoma.


You must not take Alcohol with Promazine. Your drowsiness will pose a marked danger to you when combining alcohol with Promazine. Combining Promazine with recreational drugs is also not recommended.


Promazine is not recommended in pregnancy or the breastfeeding stage. It is believed that Promazine can cause withdrawal symptoms in breastfed babies.


Other Typical Antipsychotics: